About one in eight women in countries such as the U.S. are expected to develop invasive breast cancer in their lifetime.
Some 107 genes already linked to breast cancer were confirmed while scientists found 72 new ones.
Of the variants uncovered by the team and reported in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast cancer and a further seven predispose specifically to oestrogen-receptor negative breast cancer - the subset of cases that do not respond to hormonal therapies, such as the drug tamoxifen.
By comparing breast cancer tissue with healthy breast tissue, Cleveland Clinic researchers found there was an imbalance of bacteria. If their theory is proven, it may explain why the majority of breast cancers have no genetic ties. For the study, researchers examined the tissues of 78 patients who underwent mastectomies related to breast cancer. We are thrilled to run the same campaign again in 2017 - purchasing a new or used vehicle from any Brown's store during the entire month of October will help Brown's donate a portion of the proceeds to Susan G. Komen affiliates and the Virginia Breast Cancer Foundation.
"We need to be a bit careful with genetic testing".More news: Antonio Conte hails Chelsea's spirit, commitment in Watford win
The studies involved collaborators from 300 different institutions, including the University of Cambridge, University Laval in Quebec and Harvard TH Chan School of Public Health.
'This should provide guidance for a lot of future research, ' he added.
In 2017, it is estimated that 17,586 women and 144 men will be diagnosed with breast cancer, according to Breast Cancer Network Australia.
However, not all cancer cells carry this receptor - these are known as oestrogen-receptor negative.
By analysing the 180 regions of the genome where are located some of the variations that predispose to breast cancer, it will be possible to determine the risk of a woman developing this cancer.More news: Storm Brian set to batter Britain just days after Ophelia
Felicia Harden-Bradford never thought she would get breast cancer, because she didn't have a family history.
Among breast cancer sufferers, those who rely on herbs, homeopathy or energy crystals to beat their disease are 5.68 times more at risk of an early death, a study found.
Professor Jacques Simard, from Laval University in Quebec city, Canada, another member of the global team, said: 'Using data from genomic studies, combined with information on other known risk factors, will allow better breast cancer risk assessment, therefore helping to identify a small but meaningful proportion of women at high risk of breast cancer.
Lifestyle changes such as diet, body weight, exercise and alcohol consumption are some of the modifiable risk factors for this disease.More news: Lego's official 'Women of NASA' set goes on sale November 1