Following the withdrawals of defending champion Stan Wawrinka (knee), Novak Djokovic (elbow) Kei Nishikori (wrist), Milos Raonic (wrist), Murray, the 2012 Open champion, said on Saturday his bad right hip won't allow him to play. "I was actually practicing O.K. the last few days, but it's too sore for me to win the tournament, and ultimately that's what I was here to try and do".
"Obviously had the issue with the hip ... since my match with Stan in Paris", Murray said.
Five of the top 11 men in the ATP rankings will not be present when the tournament starts on Monday in Flushing Meadows. Tried resting, rehabbing, to try and get myself ready here.More news: United set for UEFA Champions League draw
"I certainly wouldn't have been hurting myself more by trying to play".
Asked if he hopes to play again this season, Murray added: "I'll definitely make a decision on that in the next few days".
The Scot also found himself on the other side of the draw to both Rafael Nadal and Roger Federer, meaning his seeded opponent in the semi-finals is German wunderkind Alexander Zverev, who is yet to reach a grand slam quarter-final.
"There has been a lot of players with injuries this year".More news: Symptoms of solar eclipse eye damage
"Look, I want to be back on court as soon as I can".
Briton Murray, a three-time Grand Slam champion whose first major title came in 2012 on the NY hardcourts, was uncertain about his status for the remainder of the season.
Murray - who has been struggling with the injury since before Wimbledon - announced the decision on Saturday, just two days before the tournament begins.
No. 5 seed Marin Cilic moves to Murray's position at the bottom of the draw.More news: Walmart Teams With Google On Voice Activated Shopping
The lucky loser is Lukas Lacko (that nearly rhymes).